pyrimidine, 2-iodo- - Names and Identifiers
pyrimidine, 2-iodo- - Physico-chemical Properties
Molecular Formula | C4H3IN2
|
Molar Mass | 205.98 |
Density | 2.102±0.06 g/cm3(Predicted) |
Melting Point | 30-32 °C |
Boling Point | 277.4±23.0 °C(Predicted) |
Flash Point | 121.6°C |
Vapor Presure | 0.00766mmHg at 25°C |
Appearance | Crystalline powder |
Color | White to Orange to Green |
pKa | -1.18±0.13(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
Refractive Index | 1.641 |
pyrimidine, 2-iodo- - Introduction
Nature:
2-Iodopyrimidine is a solid compound with a colorless to slightly yellow crystalline appearance. Its melting point is about 78-82 degrees Celsius. The compound is soluble in organic solvents such as ethanol, acetone and dimethylformamide under certain conditions.
Use:
2-Iodopyrimidine is often used as a raw material or intermediate in organic synthesis reactions. It can be used to synthesize complex organic molecules with biological activity, such as drugs and pesticides. In addition, it is often used in the synthesis of coordination compounds, as well as for dyes and photochemistry.
Method:
In General, 2-Iodopyrimidine can be prepared by reacting pyrimidine iodide with a reducing agent. Among them, pyrimidine iodide is an intermediate obtained by reacting pyrimidine with iodide. Under typical reaction conditions, pyrimidine iodide is first reacted with a suitable reducing agent such as sodium sulfite or sodium borohydride in an organic solvent to give 2-Iodopyrimidine.
Safety Information:
2-Iodopyrimidine needs to pay attention to safety when operating. It is a potentially toxic compound that can be harmful to the human body. During use, the necessary safety measures should be followed, such as wearing protective gloves, goggles and laboratory coats. In addition, avoid contact with skin and eyes, and operate in well-ventilated conditions. In the event of exposure or ingestion, seek medical help immediately and show the substance's safety data sheet to your doctor.
Last Update:2024-04-09 20:52:54